BRAIN NAPLEX EXAM | VALID NAPLEX TEST MATERIALS

Brain NAPLEX Exam | Valid NAPLEX Test Materials

Brain NAPLEX Exam | Valid NAPLEX Test Materials

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Tags: Brain NAPLEX Exam, Valid NAPLEX Test Materials, Most NAPLEX Reliable Questions, NAPLEX Testking Exam Questions, NAPLEX Real Dumps

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NABP North American Pharmacist Licensure Examination Sample Questions (Q15-Q20):

NEW QUESTION # 15
Which of the following NSAIDs is an Enolic acid derivative?

  • A. Fenoprofen
  • B. Piroxicam
  • C. Oxaprozin
  • D. Naproxen
  • E. Ibuprofen

Answer: B

Explanation:
Explanation
The following NSAIDs belong to the propionic acid derivatives group - Ibuprofen - Ketoprofen - Naproxen - Fenoprofen - Flurbiprofen - Oxaprozin whereas piroxicam belongs to the class of Enolic acid derivative which also includes other agents like meloxicam and Nabumetone. They are non-selective COX inhibitors and act by preventing the production of certain prostaglandins.


NEW QUESTION # 16
A 22-year-old woman adopted a cat. Shortly thereafter, she developed itchy eyes and persistent rhinorrhea.
She was clearly allergic to the pet, but desperately wanted to keep it. She tried taking diphenhydramine, but it had intolerable side effects.
Which of the following is a common effect of this type of medication?

  • A. Diarrhea
  • B. Excessive sweating
  • C. Decreased intraocular pressure
  • D. Bradycardia
  • E. Xerostomia

Answer: E

Explanation:
Explanation
Diphenhydramine possesses anticholinergic properties. Xerostomia, or dry mouth, is a common side effect of anti-cholinergic medications, due to anti-muscarinic, parasympatholytic effects. Other adverse reactions may include: * Mydriasis with blurred vision, photophobia * Urinary retention * Constipation * Anhidrosis * Hyperthermia * Tachycardia * Altered mental status A commonly referenced mnemonic for anti-cholinergic toxicity is "mad as a hatter, red as a beet, dry as a bone, hot as a hare, blind as a bat" to reflect confusion, flushing, dry mouth, hyperthermia and mydriasis, respectively.


NEW QUESTION # 17
Which of the following class of antidiabetic medication may cause fluid retention?

  • A. Alpha-glucosidase inhibitor
  • B. Bile acid sequestrant
  • C. GLP-1 agonist
  • D. SGLT2 Inhibitor
  • E. Thiazolidinediones

Answer: E

Explanation:
Thiazolidinediones may cause fluid retention through proposed mechanism of increasing reabsorption in the collecting duct of the kidney and increasing vascular permeability in adipose tissue. Bile acid sequestrants work in the intestine to bind bile acids which doesn't affect fluid retention. GLP-1 receptor agonists work to activate these receptors to secrete insulin from beta pancreatic cells/decrease glucagon secretion/ increase satiety and doesn't affect fluid retention. SGLT2 inhibitors actually cause increase of fluid elimination through the kidneys.
Alpha-glucosidase inhibitors work in the gut to decrease carb absorption/digestion and have no affect on fluid retention.


NEW QUESTION # 18
If a patient takes 0.5mg of intravenous hydromorphone every 4hrs what would be the equivalent orals total daily dose? Hydromorphone oral to parenteral ratio 7.5:1.5.

  • A. 15mg
  • B. 20mg
  • C. 7.5mg
  • D. 10mg
  • E. 5mg

Answer: A

Explanation:
To determine the dose conversion IV to PO, the ratio of PO to IV needs to be determined, this is 7.5 / 1.5 which is 5. This number means that the PO dose is 5 times more than the IV dose to get the same amount of drug into the bloodstream. If the patient is taking 0.5 mg IV then the PO dose would be 0.5 mg multiplied by 5, which is 2.5 mg. Since the patient is taking the medication every 4 hours the patient is receiving 6 doses, 24hrs/4hrs
= 6. Since the patient is receiving 2.5 mg every dose and is receiving 6 doses a day, the patient is receiving 15 mg, 2.5 mg multiplied by 6 doses.


NEW QUESTION # 19
What is the Osmolarity in mOsm/L of 40mEq of KCl in 100ml sterile water? (Molecular weight of KCl is
74.5gm/ mol.)?

  • A. 200mOsm/L
  • B. 400mOsm/L
  • C. 80mOsm/L
  • D. 1600mOsm/L
  • E. 800mOsm/L

Answer: E

Explanation:
Explanation
40mEq * 1equiv/1000mEq * 74.5g/1equiv = 2.98 gm of KCl in 100ml. Calculate: mOsm/L. 2.98g/100ml *
1mol/74.5g * 2Osm/1mol * 1000mOsm/ Osm * 1000ml/1L = 800mOsm/L


NEW QUESTION # 20
......

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